Advanced Maternal Age and Adverse Perinatal Outcomes – One Decade Analysis

Authors : Seda KESKİN

Pages : 11-15

Doi:10.19127/mbsjohs.542026

View : 12 | Download : 7

Publication Date : 2019-04-28

Article Type : Research Paper

Abstract :Objective: To appoint the risk of stillbirth and the other adverse maternal and perinatal outcomes in women of AMA insert ignore into journalissuearticles values(Advanced maternal age); that traditionally described as pregnancy in women aged 35 years or older. Methods: Our study was a retrospective investigation of all women with singleton pregnancies who gave birth at > 20 weeks’ gestation aged 35 - 39 years old insert ignore into journalissuearticles values(early advanced maternal aged group, group I, n=926);, aged 40 - 49 years old insert ignore into journalissuearticles values(late advanced maternal aged group, group II, n=184); and aged 20 - 35 years old insert ignore into journalissuearticles values(control group, group III, n=1110); between January 2008 and January 2018. Parameters such as age, parity, fetal sex, fetal birth weight, birth pattern insert ignore into journalissuearticles values(cesarean and vaginal delivery); were examined. The variables investigated to determine perinatal outcomes were low birth weight, macrosomic fetus and stillbirth frequency. Results: Advanced maternal aged birth ratio to all births was 4.5 %. 83.4% of the advanced age group were the early advanced maternal aged. The low birth weight rate was significantly higher in the AMA group insert ignore into journalissuearticles values(8.6 % - 5.9 %); insert ignore into journalissuearticles values(p=0.042);. At the same time, the rate of macrosomia was significantly higher in the AMA group too. insert ignore into journalissuearticles values(9.5 % - 9.1 %); insert ignore into journalissuearticles values(p=0.042);. The rate of caesarean delivery was significantly higher in AMA group insert ignore into journalissuearticles values(63.7 % - 56.4 %);. The stillbirth rate was significantly higher in AMA group insert ignore into journalissuearticles values(1,6 % - 0,5 %); insert ignore into journalissuearticles values(p=0.005);. In group II; male gender was lower insert ignore into journalissuearticles values(47.3 % - 55 %); insert ignore into journalissuearticles values(p=0.034);, stillbirth rate was higher insert ignore into journalissuearticles values(3.8 % - 1.2 %); insert ignore into journalissuearticles values(p=0.019);, birth weight was lower insert ignore into journalissuearticles values(3193 - 3287); insert ignore into journalissuearticles values(p=0.048);. Conclusion: The risk of stillbirth was significantly higher in the late advanced maternal aged group. Pregnancies over 35 years of age are high-risk pregnancies necessitating more careful antenatal follow-up in which follow-up of pregnancy must be done more carefully. National mother friendly health policies must focus more on AMA pregnancies. More research is needed to find suitable and well-timed interventions to decrease adverse maternal and also perinatal outcomes.
Keywords : Advanced maternal age, stilbirth, high risk pregnancies