The effect of Enterobius vermicularis infection (oxyuriasis) on eosinophil and IgE levels in allergic rhinitis

Authors : Fevzi Solmaz, Oğuzhan Dikici, Davut Akduman, Mehmet Haksever, İsmail Necati Hakyemez, Muhammed Yanılmaz

Pages : 399-404

Doi:10.18621/eurj.344495

View : 18 | Download : 5

Publication Date : 2018-10-04

Article Type : Research Paper

Abstract :Objective: Elevated levels of serum IgE and eosinophilia are the indicators of atopy and intestinal parasitic infections. We evaluated the effect of Enterobius vermicularis infection insert ignore into journalissuearticles values(enterobiasis); on blood eosinophil count and IgE levels in allergic rhinitis. Methods: A total of 110 patients diagnosed with allergic rhinitis insert ignore into journalissuearticles values(with symptoms of rhinorrhea, itchy nose and nasal congestion); consisting of 41 insert ignore into journalissuearticles values(37.27%); males and 69 insert ignore into journalissuearticles values(62.73%); females were examined. Forty-one insert ignore into journalissuearticles values(37.27%); patients with enterobiasis were selected as the study group. The remaining 69 insert ignore into journalissuearticles values(62.73%); patients accepted as the control group. Results: In the study group the mean serum total IgE level and mean serum eosinophil count were 393.10 ± 159.83 IU/mL and 0.56 ± 0.04 10 3 /mL, respectively. In the control group the mean serum total IgE level and mean serum eosinophil count were 236.91 ± 63.55 IU/mL and 0.37 ± 0.12 10 3 /mL, respectively. The difference between the two groups was statistically significant for serum total IgE levels insert ignore into journalissuearticles values( p < 0.05); but not for serum eosinophil count insert ignore into journalissuearticles values( p > 0.05);. The correlation coefficients between serum total IgE level and eosinophil count were statistically insignificant insert ignore into journalissuearticles values( p > 0.05);. Conclusions : More comprehensive and long-term placebo-controlled studies should be performed in order to find the answer to the question of whether helminth infections play a role in allergic disease. 
Keywords : Enterobius vermicularis infection, allergic rhinitis, serum IgE level, serum eosinophil count