The association of carotid intima-media thickness with body mass index and cortisol level in fibromyalgia syndrome

Authors : Tuba Tülay Koca, Ayla Çimen

Pages : 83-87

Doi:10.18621/eurj.376343

View : 12 | Download : 8

Publication Date : 2019-01-04

Article Type : Research Paper

Abstract :Objectives:   Patients with fibromyalgia syndrome insert ignore into journalissuearticles values(FMS); may have the risk for atherosclerotic disease because of chronic stress, disrupted neuroendocrine axis, high BMI and inflammation. This is study aimed to research the stress and the stress-related diseases in patients with FMS by measuring obesity, morning serum cortisol level, and carotid intima-media thickness insert ignore into journalissuearticles values(CIMT);, which is the early indicator of the atherosclerosis. Methods:  This case-control study included 57 patients who were diagnosed with FMS according to 2010 American College of Rheumatology insert ignore into journalissuearticles values(ACR); Criteria and visited the outpatient clinic in February 2016. As a control group, 36 healthy females who visited the outpatient clinic in the same month were included. Carotid intima-media thickness and cortisol levels were analysed. Results:  The present study included 93 females between 15 and 79 years old. The mean age of the 57 females with FMS and 37 healthy females was 44.5 ± 10.6 years and 47.9 ± 18.5 years, respectively insert ignore into journalissuearticles values( p = 0.260);. The mean CIMT value of the FMS and control groups was 0.64 ± 0.17 mm and 0.59 ± 0.16 mm, respectively insert ignore into journalissuearticles values( p = 0.170);. The morning blood cortisol level in the FMS and control groups was 7.8 ± 3.3 ng/dL and 8.7 ± 2.8 ng/dL, respectively insert ignore into journalissuearticles values( p = 0.460);. The CIMT and morning blood cortisol level were not correlated in the FMS group. Conclusion:  According to the present study, CIMT value and morning blood cortisol level were not found significantly different in FMS group, and also were not  found correlated with each other. 
Keywords : Atherosclerosis, carotid intima media thickness, fibromyalgia syndrome