Neurological findings in autosomal dominant polycystic kidney disease

Authors : Demet YILDIZ, Abdülmecit YILDIZ

Pages : 94-97

Doi:10.18621/eurj.379970

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Publication Date : 2019-01-04

Article Type : Research Paper

Abstract :Objective:  Autosomal dominant polycystic kidney disease insert ignore into journalissuearticles values(ADPKD); mainly affects the kidneys, but other abnormalities like intracranial aneurysms insert ignore into journalissuearticles values(ICAs); are not uncommon. In this study, we aimed to investigate retrospectively frequency of ICA and other neurological abnormalities in ADPKD patients. Methods:  One hundred and forty patients with ADPKD who did not receive replacement therapy and followed-up at outpatient clinic were evaluated. Results:  The mean age of the patients was 43.4 ± 13 years and mean glomerular filtration rate was 87 ± 15 ml/min. ICA was detected in four insert ignore into journalissuearticles values(2.8%); patients. Three patients were from the same family. Thirteen insert ignore into journalissuearticles values(9.3%); patients had magnetic resonance angiography due to their family stories, but aneurysm was not seen in them. Conclusion:  Individuals with ADPKD who have a history of aneurysm or hemorrhage in their family should be screened for aneurysm due to mortality and risk of recurrent rupture. 
Keywords : Autosomal dominant, polycystic kidney disease, intracranial aneurysms, arachnoid cysts