Should anaesthesia method for prostate biopsy be the same for every patient? A randomised prospective study to determine the risk factors for pain

Authors : Sinan AVCI, Sedat ONER, Efe ÖNEN, Volkan ÇAĞLAYAN, Metin KILIÇ, Murat ŞAMBEL

Pages : 470-478

Doi:10.18621/eurj.519668

View : 17 | Download : 11

Publication Date : 2020-09-04

Article Type : Research Paper

Abstract :Objectives: To evaluate the risk factors for pain occurring during prostate biopsy. Methods: This study included 123 patients were applied with prostate needle biopsy under transrectal ultrasonography. The patients were randomly separated into 3 groups of 41 individuals. For periprostatic nerve blockage, 10 cc 2% lidocaine was applied to Group 1, 10 cc 0.25% levobupivacaine to Group 2, and 10 cc 0.25% bupivacaine to Group 3. A 10 cm Visual Analogue Scale insert ignore into journalissuearticles values(VAS); was used to evaluate patient pain. The pain of the patients was evaluated in 4 stages. VAS 1: Pain score during the injection of the anaesthetic agent; VAS 2: Pain score during the biopsy when half the procedure was completed; VAS 3: Pain score following removal of the rectal probe immediately after the biopsy; and VAS 4: Pain score at 1 hour after the biopsy. Results: There were significant negative correlations between VAS 3 pain scores and age in group 1, group 3 and for entire cohort insert ignore into journalissuearticles values( p = 0.013, p = 0.031 and p = 0.033, respectively);. In group 1 both total and free PSA showed significant negative correlations with VAS 3 pain scores insert ignore into journalissuearticles values( p = 0.020 and p = 0.010, respectively);. In group 2 VAS 4 pain scores of the patients with suspicious digital examination findings were found to be significantly higher than those of the patients with benign digital examination findings insert ignore into journalissuearticles values( p = 0.025);. Conclusions: Of all patients to be applied with prostate biopsy, those of a younger age, with a lower PSA level, with suspicious digital rectal examination findings constitute a relatively higher risk group in respect of pain. 
Keywords : biopsy, pain, prostate, risk factors