Evaluation of infections in patients with kidney and liver transplantation

Authors : Sibel DOĞAN KAYA, Güliz EVİK, Münire DENİZ, Yeşim UYGUN KIZMAZ

Pages : 1093-1098

Doi:10.18621/eurj.1340605

View : 38 | Download : 48

Publication Date : 2023-09-04

Article Type : Research Paper

Abstract :Objectives: Infection is a frequent complication of organ transplantation and is associated with significant morbidity and mortality. Methods: Patients who had liver and kidney transplants between 2011 and 2022, who were hospitalized in our hospital, and who were consulted for infectious diseases were retrospectively analyzed from hospital records. Results: Of the patients included in the study, 9 insert ignore into journalissuearticles values(28%); were female, 23 insert ignore into journalissuearticles values(72%); were male, and the mean age was 33.7 ± 11.3 years. Patients had congestive heart failure insert ignore into journalissuearticles values(87.2%, n = 28, hypertension insert ignore into journalissuearticles values(43.7%, n = 14);, and chronic obstructive pulmonary disease insert ignore into journalissuearticles values(21.8%, n = 7);. Twenty insert ignore into journalissuearticles values(62.5%); kidney transplant recipients and 12 insert ignore into journalissuearticles values(37.5%); liver transplant recipients were seen within ten years. The most common infections were urinary tract infection in 8 insert ignore into journalissuearticles values( 25%); patients and pneumonia in 11 insert ignore into journalissuearticles values(34.3%);. The other infections were gastrointestinal infections such as diarrhoea, bloodstream infections and COVID-19 and Cytomegalovirus. Culture-isolated organisms in 20 insert ignore into journalissuearticles values(62.5%); of the 32 patients admitted with infections. The microbiological data were notable for some unusual and opportunistic pathogens, including one case of acute cytomegalovirus viremia. Severe sepsis had been seen in six insert ignore into journalissuearticles values(18.75%); out of 32 patients with documented infections. Conclusions: Infection prevention has become a cornerstone of modern transplantation medicine due to the significant incidence of post-transplant infectious complications resulting from improved immunosuppressive therapies and surgical procedures.
Keywords : Liver transplantation, renal transplantation, infectious disease, post transplant infections