Predictive role of ABCD2, ABCD3I, C-reactive protein, neutrophil-lymphocyte ratio, platelet-lymphocyte ratio and systemic immune-inflammation index in 90-day and long-term stroke after transient ischemic attack

Authors : İdris KOCATÜRK, Sedat GÜLTEN

Pages : 1207-1214

Doi:10.18621/eurj.1341008

View : 36 | Download : 50

Publication Date : 2023-09-04

Article Type : Research Paper

Abstract :Objectives: Transient ischemic attack insert ignore into journalissuearticles values(TIA); is a neurological emergency and a precursor of ischemic stroke. ABCD2 and ABCD3I scores predict stroke after TIA, and clinicians use preclinical, clinical, and radiological parameters for calculating these scores. Our study aimed to investigate the efficacy of peripheral blood markers in predicting 90-day and long-term stroke risk after TIA. Methods: This retrospective study was conducted in Kastamonu Training and Research Hospital between January 2015 and November 2022. The demographic data of 99 patients who applied with the diagnosis of TIA and peripheral blood markers at the time of first admission to the hospital were used in the study. These parameters was evaluated in 90-day and long-term insert ignore into journalissuearticles values(>12 months); stroke after TIAs. Results: Of the 99 patients in our study, 59% insert ignore into journalissuearticles values(n = 58); were male. The mean age of the patients was 70 ± 13 years. ABCD2 insert ignore into journalissuearticles values(age, blood pressure, clinical features, duration of symptoms, and presence of diabetes mellitus); and ABCD3I insert ignore into journalissuearticles values(age, blood pressure, clinical features, duration of symptoms, presence of diabetes mellitus, dual TIA, and ipsilatheral carotis stenosis); scores and C-reactive protein insert ignore into journalissuearticles values(CRP); were statistically significant in predicting 90-day stroke. ABCD2 and ABCD3I were not effective in predicting long-term stroke. In addition, CRP, neutrophil-lymphocyte ratio insert ignore into journalissuearticles values(NLR);, platelet-lymphocyte ratio insert ignore into journalissuearticles values(PLR);, and systemic immune-inflammation index insert ignore into journalissuearticles values(SII); parameters were statistically significant in long-term stroke. CRP insert ignore into journalissuearticles values(AUC=793, sensitivity=82%, and specificity=81%); values were higher than ABCD2 insert ignore into journalissuearticles values(AUC=779, sensitivity=73%, and specificity=76%); and ABCD3I insert ignore into journalissuearticles values(AUC=755, sensitivity=82%, and specificity=70%); scores in predicting 90-day stroke. Conclusions: Our study showed that ABCD2, ABCD3I, and CRP effectively predict 90-day stroke after TIA. Furthermore, CRP was more effective than ABCD2 and ABCD3I scores in predicting 90-day stroke after TIA. CRP, NLR, PLR, and SII also effectively predicted long-term stroke after TIA.
Keywords : Transient ischemic attack, ABCD2, ABCD3I, C reactive protein