Antioxidant and antimicrobial activity of Turkish endemic Sonchus erzincanicus extracts

Authors : Ahmet MAVİ, Nimet YİĞİT, Demet YİĞİT, Ali KANDEMİR

Pages : 243-250

View : 14 | Download : 3

Publication Date : 2011-12-01

Article Type : Research Paper

Abstract :Sonchus erzincanicus insert ignore into journalissuearticles values(Asteraceae); is a plant species that is endemic to Turkey and grows in Erzincan. Lipid peroxidation inhibition, 2,2-diphenyl-1-picrylhydrazyl insert ignore into journalissuearticles values(DPPH); radical scavenging activity, and total phenolic content of the methanol and water extracts of the plant were determined. Antimicrobial activity of the extracts was also tested against 107 clinical isolates of human pathogenic microorganism strains belonging to Enterobacter aerogenes, Escherichia coli, Proteus mirabilis, Pseudomonas aeruginosa, Staphylococcus aureus, and Candida albicans using the disc-diffusion method, and the minimal inhibition concentration insert ignore into journalissuearticles values(MIC); value of each active extract was determined. The extracts were observed to have antioxidant potential, although no better than that of BHT insert ignore into journalissuearticles values(butylated hydroxytoluene);, which is a well-known commercial antioxidant. The extracts exhibited antimicrobial effects on all the tested microorganism species, except for P. aeruginosa and E. aerogenes. In addition, antifungal activity of the methanol extract against C. albicans was better than that of the water extract insert ignore into journalissuearticles values(inhibition zone: 25 mm; MIC: 0.156 mg/mL);. As a consequence, it was observed that the methanol and water extracts of Sonchus erzincanicus had in vitro lipid peroxidation inhibition and antimicrobial effects against some microorganisms.
Keywords : Key words Sonchus erzincanicus, antioxidant activity, antimicrobial activity