The Antioxidant Activity of Some Medicinal Plants

Authors : Prateek Kumar JAIN, Veerasamy RAVICHANDRAN, Simant SHARMA, Ram K. AGRAWAL

Pages : 197-202

View : 8 | Download : 7

Publication Date : 2008-12-01

Article Type : Research Paper

Abstract :The antioxidant properties of the methanol extracts of 10 medicinal plants were evaluated with the DPPH insert ignore into journalissuearticles values(1,1-diphenyl-2-picryl hydrazyl); test, hydroxyl scavenging test, and lipid peroxidation assay. The methanol extract of Emblica officinalis was the most active according to the DPPH test, with an IC50 value of 7.92 ± 0.1 mg/ml, followed by Asparagus racemosus, with an IC50 value of 9.28 ± 0.2 mg/ml. The minimum free radical scavenging activity was shown by Zingiber officinale, with an IC50 value of 44.48 ± 1.8 mg/ml. The hydroxyl radical scavenging activity of the methanolic extracts of various plants was as follows: Asparagus racemosus > Terminalia chebula > Emblica officinalis > Centella asiatica > Withania somnifera > Terminalia bellerica > Glycyrrhiza glabra > Evolvulus alsinoides > Zingiber officinale > Andrographis paniculata. According to the lipid peroxidation assay the extracts of Emblica officinalis and Evolvulus alsinoides showed the greatest effectiveness, with inhibition values of 39.14 ± 2.1% and 36.38 ± 1.3%, respectively, at the 100-mg/m concentration insert ignore into journalissuearticles values(P < 0.05);. Results of the present study suggest that all the tested plant materials had moderate to potent antioxidant activity.
Keywords : Antioxidants, DPPH assay, lipid peroxidation assay, medicinal plants