Activity of antioxidant enzymes in the liver of wild boars (Sus scrofa) from a selenium-deficient area depending on sex, age, and season of the year

Authors : Dorota JANKOWIAK, Renata PILARCZYK, Radoslaw DROZD, Bogumila PILARCZYK, Agnieszka TOMZA-MARCINIAK, Gabriela WYSOCKA, İzabella RZAD, Arleta DROZD, Jaroslaw KUBA

Pages : 129-138

Doi:10.3906/biy-1405-52

View : 13 | Download : 4

Publication Date : 2015-12-01

Article Type : Research Paper

Abstract :The aim of this study was to compare the activity of antioxidant enzymes superoxide dismutase insert ignore into journalissuearticles values(SOD);, catalase insert ignore into journalissuearticles values(CAT);, and total and selenium-dependent glutathione peroxidase insert ignore into journalissuearticles values(total GSH-Px and Se-GSH-Px); in the liver of wild boars insert ignore into journalissuearticles values(Sus scrofa); selected from a selenium-deficient area with respect to season of the year, sex, and age. Only season had a significant effect on liver Se content. Liver selenium concentration in the wild boars was highest in spring insert ignore into journalissuearticles values(0.292 µg/g wet weight); and lowest in winter insert ignore into journalissuearticles values(0.185 µg/g wet weight); insert ignore into journalissuearticles values(P < 0.05);. The highest mean activity of total GSH-Px, Se-GSH-Px, and CAT insert ignore into journalissuearticles values(404.0, 309.9, and 1170.0 U/mg protein, respectively); was found in the spring season, and the respective highest mean activity of SOD was found during autumn insert ignore into journalissuearticles values(31.5 U/mg protein);. Females showed markedly higher mean activities of total GSH-Px insert ignore into journalissuearticles values(388.2 and 314.7 U/mg protein); and CAT insert ignore into journalissuearticles values(1151.0 and 765.8 U/mg protein); compared to males. In comparison to other groups of animals, those aged between 1 and 1.5 years were characterized by higher mean activity of total GSH-Px and Se-GSH-Px, and those over 2 years of age showed higher activity of CAT and SOD. The analysis showed that the strongest oxidative stress and the greatest risk of peroxidative damage to the liver occurred during the winter.
Keywords : Liver, wild boar, selenium, antioxidant enzymes, seasons of the year