A novel naphthoquinone glycoside from Rubia peregrina L.

Authors : Ufuk ÖZGEN, Cavit KAZAZ, Hasan SEÇEN, İhsan ÇALIŞ

Pages : 561-568

View : 13 | Download : 6

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :A phytochemical study was performed on the subterranean parts insert ignore into journalissuearticles values(roots and rhizomes); of Rubia peregrina. The substances were isolated from chloroform, ethyl acetate, and water soluble parts of the methanolic extract using several chromatographic techniques. 1-Hydroxy-2-methyl-9,10-anthraquinone insert ignore into journalissuearticles values(1);, 1,3-dihydroxy-2-methyl- 9,10-anthraquinone insert ignore into journalissuearticles values(2);, and 1,3-dihydroxy-2-methoxymethyl-9,10- anthraquinone insert ignore into journalissuearticles values(3); were isolated from the chloroform phase; and asperuloside insert ignore into journalissuearticles values(4);, asperulosidic acid insert ignore into journalissuearticles values(5);, rubiadin 3-O-b-primeveroside insert ignore into journalissuearticles values(6);, lucidin 3-O-b -primeveroside insert ignore into journalissuearticles values(7);, deacetylasperulosidic acid insert ignore into journalissuearticles values(8);, liriodendrin insert ignore into journalissuearticles values(9);, and a new naphthoquinone glycoside, 2-hydroxy-3-O-b-primeveroside naphthalene-1,4-dione insert ignore into journalissuearticles values(inkumoside, 10);, from the aqueous phase. The structures of the compounds were elucidated by means of spectral analysis insert ignore into journalissuearticles values(1H-NMR, 13C-NMR, 2D-NMR--COSY, HMBC, HMQC-, EI-MS and ESI-MS);.
Keywords : Rubia peregrina, Rubiaceae, anthraquinones, iridoid glycosides, naphthoquinone glycoside