Synthesis and Biological Activity of Allosteric Modulators of GABAB Receptors. Part 4. Synthesis of Potentially Fluorescent Acridines and Conformationally Restricted N-(arylpropyl)-1-arylethylamines

Authors : Jabbar KHALAFY, Rolf H. PRAGER and Ni Made PUSPAWATI, Rolf H. PRAGER

Pages : 755-763

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Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :A series of 8 new derivatives of fendiline was prepared for evaluation as allosteric modulators of GABAB receptors: 4 based on acridine and 4 with restricted distance between the 2 aryl moieties.
Keywords : Fendiline analogues, acridines, acridones, aminotetralins, aminoindanes, GABA