Studies on the Chemical Constituents of Thymus serpyllum

Authors : Shahid AZIZ

Pages : 605-614

View : 11 | Download : 4

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :Phytochemical investigations on the methanolic extract of Thymus serpyllum resulted in the isolation of 2 new compounds, 3-ketopentatriacontanoic acid insert ignore into journalissuearticles values(1); and 27-ketotriacontanol insert ignore into journalissuearticles values(2);. The extract also afforded 3 known compounds, 3 b-hydroxyolean-12-en- 28-oic acid insert ignore into journalissuearticles values(3);, 3-O-b-D-glucopyranosyl-sitosterol insert ignore into journalissuearticles values(4);, and dihydroursonic acid insert ignore into journalissuearticles values(5);, detected for the first time from Thymus serpyllum. The structures of the new compounds were elucidated by spectroscopic methods, while the known compounds were identified on the basis of their spectral data and literature evidence. The hexane and ethyl acetate soluble portions of the methanolic extract showed significant antifungal activity, whereas the chloroform soluble portion and the remaining methanol extract showed moderate activity.
Keywords : Thymus serpyllum, chemical constituents, isolation, structures, antifungal