Zinc Perchlorate Hexahydrate Catalyzed Mono- and Bis-Transesterification of Malonic Esters

Authors : Servet TURAL

Pages : 169-179

View : 12 | Download : 5

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :Commercially available zinc perchlorate hexahydrate [Zninsert ignore into journalissuearticles values(ClO4);2.6H2O] was found to be a highly effective catalyst for the transesterification of malonic esters with alcohols. The treatment of methyl-, ethyl-, or a-substituted malonic esters with primary or secondary alcohols in the presence of a catalytic amount of zinc perchlorate results in good to high yields of the corresponding esters insert ignore into journalissuearticles values(68%-99%);. Mono-transesterification products are also obtained in moderate to good yields insert ignore into journalissuearticles values(22%-42%);. The reaction was also carried out with 2-mono- and di-substituted malonic esters, and in the case of 2-mono- and di-substituted malonic esters, the reaction time is, in some cases, shorter, in which the yields are comparable with unsubstituted derivatives. The cyanomethyl and bis-cyanomethyl malonic ester derivatives are also used for transesterification and the corresponding products are obtained in high yields. No reaction occurs with the CN group during the reaction.
Keywords : Transesterification, zinc perchlorate, malonic esters, mono substituted malonic esters, unsymmetrical malonic esters