Organotin (IV) Derivatives of 1-Ethyl-1,4-Dihydro-7- Methyl-4-Oxo-1,8-Naphthyridine-3-Carboxylic Acid (Nalidixic Acid): Synthesis, Structural Elucidation and Biological Activities

Authors : Sajjad AHMED, Moazzam Hussain BHATTI, Saqib ALI

Pages : 193-202

View : 10 | Download : 3

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :Organotin carboxylates of the general formulae R2SnL2 and R3SnL, where R = CH3, n-C4H9, C6H5, CH2C6H5 and L = 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid insert ignore into journalissuearticles values(nalidixic acid);, have been prepared. These compounds were characterized by FT-IR, mass and multinuclear NMR insert ignore into journalissuearticles values(1H, 13C and 119Sn); spectroscopy. The geometry around the tin atom is compared both in solution and in solid state. These compounds were also screened for their antifungal and antibacterial activities.
Keywords : Organotin IV, complexes, 1 ethyl 1, 4 dihydro 7 methyl 4 oxo 1, 8 naphthyridine 3 carboxylic acid nalidixic acid, , Spectroscopic characterization, Biological Act