Studies on the Methylation of 5-Nitro-benzimidazoles

Authors : Mashooda HASAN, Farzana SHAHEEN and Uzma YUNUS

Pages : 73-80

View : 9 | Download : 6

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :Methylation of 2H, 5-nitro- insert ignore into journalissuearticles values(1); and 2-ethyl, 5-nitro- insert ignore into journalissuearticles values(2); benzimidazoles separately with methyl iodide in acetone in the presence of potassium carbonate yielded 2H, 5/6-nitro-insert ignore into journalissuearticles values(3A and 3B); and 2-ethyl, 5/6-nitro- insert ignore into journalissuearticles values(4A and 4B); methylbenzimidazoles respectively. Methylation of 1 and 2 in dimethylformamide in place of acetone yielded not only 3A, 3B and 4A, 4B respectively, but in addition 1,3-dimethyl-5-nitro-benzimidazol-2-one insert ignore into journalissuearticles values(5); was also obtained in each case. The structure of the synthesized compounds was determined with the help of mass and 1H NMR spectroscopic analysis.
Keywords : Turk J Chem, 24, 2000, , 73 80 Turk J Chem, vol 24, iss 1