Synthesis, spectral characterisation, electrochemical, and fluorescence studies of biologically active novel Schiff base complexes derived from E-4-(2-hydroxy-3- methoxybenzlideneamino)-N-(pyrimidin-2-yl)benzenesulfonamide

Authors : Valarmathy GOVINDARAJ, Subbalakshmi RAMANATHAN

Pages : 521-530

Doi:10.3906/kim-1301-83

View : 10 | Download : 6

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :A new Schiff base was prepared from 2-sulphanilamidopyrimidine and 2-hydroxy-3-methoxybenzaldehyde in ethanolic media and it was complexed with Mninsert ignore into journalissuearticles values(II);, Coinsert ignore into journalissuearticles values(II);, Niinsert ignore into journalissuearticles values(II);, Cuinsert ignore into journalissuearticles values(II);, and Zninsert ignore into journalissuearticles values(II); ions. The synthesised ligand and complexes were characterised by IR, UV, 1H and 13C NMR, elemental analysis, cyclic voltammetry, EPR, molar conductance, and magnetic susceptibility. The reasonable shifts in FT-IR and NMR spectral signals of the complexes with respect to the free ligand confirm good coordination of the Schiff-base ligand with the metal through imine nitrogen and oxygen atoms of Schiff base moiety. The Schiff-base ligand and the complexes were screened for antimicrobial activity and fluorescent behaviour. From the analytical and spectral data, the stoichiometry was found to be 1:2 for all the complexes. An octahedral structure was proposed. All the complexes were found to be active against bacteria and fungi.
Keywords : Schiff base, 2 sulphanilamidopyrimidine, 2 hydroxy 3 methoxybenzaldehyde, metal complexes, biological activity, fluorescent behaviour