A promising materials approach to combatting renal hyperphosphatemia: Fe(II)-montmorillonites

Authors : XIAOTONG YUAN, DAWEI QIN, MIN QIAO, Gang LIU, Hongxin LI, XIA NIU

Pages : 944-954

View : 13 | Download : 9

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :The objective of the current effort was to determine the efficacy of Feinsert ignore into journalissuearticles values(II);-montmorillonite insert ignore into journalissuearticles values(Feinsert ignore into journalissuearticles values(II);-MMT); as an adjuvant for specific targeted adsorption of phosphate. Specifically, Feinsert ignore into journalissuearticles values(II);-MMT was studied to combat hyperphosphatemia and anemia arising from chronic renal failure. The adsorption of phosphate over time, pH, and initial concentration was studied. The systems were characterized by X-ray diffraction insert ignore into journalissuearticles values(XRD);, Raman, and zeta potential. The experimental results demonstrated the adsorption time was set to 140 min to achieve maximum adsorption efficiency. It was thus found that the maximum adsorption was at pH 3.0. In addition, it reached equilibrium when the initial phosphate concentration was at 60 mg/L while the maximum adsorption capacity was 5.75 mg of phosphate/g of Feinsert ignore into journalissuearticles values(II);-MMT. On the other hand, adsorption isotherms showed that the Langmuir model was better than the Freundlich model. This means that the adsorption of the phosphate on Feinsert ignore into journalissuearticles values(II);-montmorillonites was monolayer adsorption, and the phosphate was successfully adsorbed either onto the surface or intercalated within interlayer volume. Live experiments supported the ability of Fe insert ignore into journalissuearticles values(II);-MMT to control hyperphosphatemia and treat chronic renal failure.
Keywords : Adsorption, phosphate, Fe II, montmorillonites, chronic renal failure, hyperphosphatemia