Antioxidant potential and secondary reactivity of bis f diphenyl(2-pyridyl)phosphino g copper(II) complex

Authors : Ezzat KHAN, Adnan SHAHZAD, Muhammad Nawaz TAHIR, Awal NOOR

Pages : 1299-1309

View : 24 | Download : 6

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :Copper-based complexes with the general formulas [Cuinsert ignore into journalissuearticles values(L); 2 ` role=`presentation`> 2 2 _{2} ]Cl 2 ` role=`presentation`> 2 2 _{2} insert ignore into journalissuearticles values( 1 ); and [Cu 2 ` role=`presentation`> 2 2 _{2} L 2 ` role=`presentation`> 2 2 _{2} insert ignore into journalissuearticles values( μ 2 ` role=`presentation`> μ 2 μ 2 \mu_{2} -L); μ 2 − ` role=`presentation`> μ 2 − μ 2 − \mu_{2-} Cl 2 ` role=`presentation`> 2 2 _{2} ] insert ignore into journalissuearticles values( 2 ); and a mixed-ligand anionic complex [Cuinsert ignore into journalissuearticles values(L); 2 ` role=`presentation`> 2 2 _{2} dedtc][LCl] insert ignore into journalissuearticles values( 3b );, where L = diphenylinsert ignore into journalissuearticles values(2-pyridyl);phosphine and dedtc = diethyldithiocarbamate, were synthesized and structurally characterized. X-ray analysis revealed that the coordination environment around the copper atom in complexes 1-3 is distorted tetrahedral. In monomeric complexes 1 and 3b both diphenylinsert ignore into journalissuearticles values(2-pyridyl); phosphine ligands are monodentate and are coordinated through the P-atom. In complex 3b two phosphine ligands are attached to copper through the P-atom. The third phosphine ligand acts as a bridged ligand, coordinated to the metal centers through the P-atom and N-atom. Complexes 1 and 3b were tested for radical scavenging activity using 2,2-diphenyl-1-picrylhydrazyl insert ignore into journalissuearticles values(DPPH); as a free radical. A prominent color change after mixing the solution of complex 1 and DPPH was observed, indicating the efficiency of the compound as antioxidant.
Keywords : Cu II, phosphine complex, secondary reactivity, dithiocarbamate, X ray structure, antioxidant agent