Anticoagulant Rodenticide Intoxication in Animals – A Review

Authors : İvan VALCHEV, Rumen BINEV, Veska YORDANOVA, Yordan NIKOLOV

Pages : 237-243

View : 9 | Download : 3

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :The newest measures for the control of harmful rodent populations are from the anticoagulant rodenticide group, which are divided into 2 subgroups: first and second generations, and indandione derivatives. Non-target organisms are potentially at risk of direct consumption of baits insert ignore into journalissuearticles values(primary hazard); and of eating poisoned rodents insert ignore into journalissuearticles values(secondary hazard);. Anticoagulant rodenticides inhibit the enzyme vitamin K-dependent carboxylase and thus impair the reactivation of vitamin K1, indirectly affecting physiological blood coagulation. The diagnosis is made on the basis of clinical signs insert ignore into journalissuearticles values(massive hemorrhages);, laboratory findings, and especially the changes in coagulation markers insert ignore into journalissuearticles values(APTT, PT, TT, PCT, ACT, FDPs, and PIVKA);. The specific antidote is vitamin K1. The general prophylaxis consists of placing baits out of reach of animals, daily control of baits and dead rodents, which are to be timely removed.
Keywords : Intoxication, anticoagulant rodenticides, animals