The Effects of in Ovo Insulin-Like Growth Factor-1 on Embryonic Development of Musculus Longus Colli Dorsalis in Japanese Quail

Authors : Turgay DEPREM, Nurhayat GÜLMEZ

Pages : 233-240

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Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :The objective of the present study was to evaluate the effects of insulin-like growth factor-1 insert ignore into journalissuearticles values(IGF-1); on the histological development of the thoracic part of the m. longus colli dorsalis insert ignore into journalissuearticles values(m. spinalis thoracis); in Japanese quail embryos. A single in ovo dose of recombinant human IGF-1 insert ignore into journalissuearticles values(rhIGF-1); insert ignore into journalissuearticles values(100 ng embryo-1); was administered through the blunt end of eggs via a single hole made with a dental drill bit, without penetrating the chorioallantoic membrane. For histological evaluation, the embryos were collected daily from days 7 to 16 of embryonic development insert ignore into journalissuearticles values(E);. In ovo administration of rhIGF-1 increased the diameter of muscle fibers on E7, 9, 10, 11, and 13. Additionally, in ovo rhIGF-1 also increased the number of muscle fibers insert ignore into journalissuearticles values(P < 0.001);. It was concluded that rhIGF-1 accelerated skeletal muscle development in the quail embryos.
Keywords : Quail, skeletal muscle development, rhIGF 1, in ovo