- Turkish Journal of Veterinary and Animal Sciences
- Volume:27 Issue:1
- The Diagnostic Importance of Erythrocyte Glutathione Peroxidase (GSH-Px) Activity and Some Serum Par...
The Diagnostic Importance of Erythrocyte Glutathione Peroxidase (GSH-Px) Activity and Some Serum Parameters in Lambs with White Muscle Disease
Authors : M. Erman OR, H. Tamer DODURKA, Abdullah KAYAR
Pages : 1-6
View : 11 | Download : 5
Publication Date : 0000-00-00
Article Type : Research Paper
Abstract :The aim of this study was to determine the diagnostic importance of erythrocyte glutathione peroxidase activity insert ignore into journalissuearticles values(GSH-Px); in lambs with white muscle disease insert ignore into journalissuearticles values(WMD); and the changes in some serum parameters insert ignore into journalissuearticles values(glucose, creatinine, total protein, albumin, cholesterol, triglyceride, Ca, inorganic P, Na, K, Cl, AST, ALT, ALP, LDH and CPK); in healthy and white muscle diseased lambs. The research was carried out on 32 lambs of which 22 showed clinical symptoms and 10 were healthy from 280 lambs raised around Esenyurt-İstanbul. The erythrocyte glutathione peroxidase activity insert ignore into journalissuearticles values(GSH-Px); was determined using the RANSEL glutathione peroxidase test by taking approximately 7 cc of anticoagulated blood from every lamb. Blood serum parameters were measured using a Technicon SMA-autoanalyzer. Clinically, it was determined that the patients could not stand up, and stumbled and trembled. It was determined that GSH-Px enzyme activity decreased insert ignore into journalissuearticles values(p < 0.01);; and serum CPK, AST, ALT, ALP, LDH enzyme levels increased insert ignore into journalissuearticles values(p < 0.01);. It was observed that lambs stood up after treatment with Selephos, which contains 30 mg sodium selenite + 1500 mg vitamin E, in 50 ml flacons with 1 ml/10 kg twice with two week intervals, in one dosage. In conclusion, it was determined that glutathione peroxidase enzyme activity insert ignore into journalissuearticles values(GSH-Px); measurement is an applicable test for the diagnosis of white muscle disease and serum CPK, AST, ALT, LDH and ALP enzyme activity measurements were significant in lambs with white muscle disease.Keywords : White Muscle Disease, Glutathione Peroxidase Activity, Blood Serum Parameters