In vitro Antibacterial Activities of Tilmicosin and Cefquinome Alone or in Combination Against Certain Poultry Pathogens

Authors : Seyyal AK

Pages : 577-580

View : 9 | Download : 3

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :The antimicrobial activities of cefquinome and tilmicosin were determined in vitro against P. multocida and O. rhinotracheale of poultry origin by serial broth macrodilution. Both antibiotics exhibited good in vitro antibacterial activity against the strains tested. The minimum inhibitory concentration insert ignore into journalissuearticles values(MIC); for cefquinome was 1.562 µg/ml and for tilmicosin was 0.78 µg/ml for both microorganisms. To investigate the effects of a combination of cefquinome and tilmicosin, the fractional inhibitory concentration insert ignore into journalissuearticles values(FIC); index was determined by checkerboard assay. The antimicrobial combination was additive against P. multocida insert ignore into journalissuearticles values(FIC=1); and indifferent against O. rhinotracheale insert ignore into journalissuearticles values(FIC=2);.
Keywords : Tilmicosin, cefquinome, combination, P multocida, O rhinotracheale