Significance of homocysteine and cardiac markers in cattle with hypocalcemia

Authors : YILDIRAY BAŞBUĞAN, NAZMİ YÜKSEK, NURİ ALTUĞ

Pages : 699-704

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Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :This study aimed to determine the levels of homocysteine and cardiac markers in cows with hypocalcemia. This research was conducted with a total of 20 cows, including 10 with hypocalcemia and 10 healthy controls. Hypocalcemia was diagnosed by determining low blood calcium insert ignore into journalissuearticles values(Ca); levels, and a standard hypocalcemia treatment was initiated in those cows with the disease. Blood samples were taken before the treatment and again 12 h after the treatment, and there was no significant difference in the homocysteine levels between the groups. Ca, ionized calcium insert ignore into journalissuearticles values(Ica);, magnesium insert ignore into journalissuearticles values(Mg);, and phosphorus insert ignore into journalissuearticles values(P); levels were lower, while cardiac troponin I insert ignore into journalissuearticles values(cTnI);, parathormone insert ignore into journalissuearticles values(PTH);, creatine kinase insert ignore into journalissuearticles values(CK);, and creatine kinase-MB insert ignore into journalissuearticles values(CK-MB); levels were higher before treatment as compared with the control group. Increases in the Ca, Mg, Ica, and P levels, and a decrease in the PTH levels were detected after treatment when compared with those levels before treatment. The CK, CK-MB, and Mg levels also increased, while the Ica level decreased in the after-treatment group as compared with the control group. Therefore, the cTnI, CK, and CK-MB in cows with hypocalcemia were determined to be important diagnostically, but insignificant for prognosis. Homocysteine was not important for either diagnosis or prognosis.
Keywords : Hypocalcemia, homocysteine, cardiac biomarkers, troponin I