Analysis of acid?base disorders in calves with lactic acidosis using aclassic model and strong ion approach

Authors : Michal BEDNARSKI, Robert KUPCZYNSKI

Pages : 615-620

View : 18 | Download : 4

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :The objective of this study was to analyze the disorders of acid-base balance in calves with lactic acidosis using the classic model and the strong ion approach. The study included 40 calves: group I was the control group insert ignore into journalissuearticles values(n = 20); and group II consisted of calves with diarrhea and lactic acidosis insert ignore into journalissuearticles values(n = 20);. The highest lactate concentration insert ignore into journalissuearticles values(5.49 ± 2.58 mmol/L); was documented in diarrheic calves. The diarrheic calves presented with significantly lower pH, pCO2, and concentrations of HCO3- insert ignore into journalissuearticles values(P < 0.01);, and with higher anion gap insert ignore into journalissuearticles values(AG);, strong ion difference insert ignore into journalissuearticles values(SID3, SID7);, and strong ion gap insert ignore into journalissuearticles values(SIG); insert ignore into journalissuearticles values(P < 0.01); than the controls. In the group of diarrheic calves lactic acid correlated with AG insert ignore into journalissuearticles values(r = 0.684, P < 0.01);, SID3 insert ignore into journalissuearticles values(r = 0.718, P < 0.01);, SID7 insert ignore into journalissuearticles values(r = 0.494, P = 0.03);, and SIG insert ignore into journalissuearticles values(r = 0.561, P = 0.01);. There was a negative correlation between lactate and effective SID insert ignore into journalissuearticles values(SIDEff); insert ignore into journalissuearticles values(r = -0.499, P = 0.02);, and total plasma concentration of nonvolatile buffers insert ignore into journalissuearticles values(ATot ); insert ignore into journalissuearticles values(r = -0.361, P = 0.04);. The results indicated that in lactic acidosis there were specific disturbances with an increased concentration of unmeasured strong ions.
Keywords : Calves, diarrhea, acid base balance, strong ion difference, lactic acidosis