Does Lymphocyte / CRP Ratio Predict Progression of Disease in Covid-19 Patients With Myocardial Injury?

Authors : Umut KARABULUT, Dilay KARABULUT

Pages : 25-26

Doi:10.46310/tjim.875857

View : 9 | Download : 6

Publication Date : 2021-03-07

Article Type : Other Papers

Abstract :Background: This study aims to reveal whether the Lymphocyte-C-reactive protein ratio insert ignore into journalissuearticles values(LCR);, a systemic inflammatory marker, predicts disease progression in COVID-19 patients with myocardial injury. Methods: A total of 172 patients,18 years and older, hospitalized due to COVID 19 between April 2020 and May 2020 in our hospital were included retrospectively. Hg, leukocyte, lymphocyte, neutrophil, thrombocyte, AST, ALT, creatinine, LDH, albumin, ferritin, triglyceride, procalcitonin, C-reactive protein, fibrinogen, D-dimer, troponin, LCR values of the patients were recorded. LRC ratios were amplified as x100. Patients were divided into two groups as with and without myocardial injury. IBM SPSS Statistics 21.0 program was used for statistical analysis. Statistically, p 0.05);. Hypertension insert ignore into journalissuearticles values(HT);, chronic renal failure insert ignore into journalissuearticles values(CRF); were more common in the group with myocardial injury insert ignore into journalissuearticles values(p <0.01, p <0.01);. Procalcitonin and creatine levels were significantly higher in the group with myocardial injury insert ignore into journalissuearticles values(p = 0.002, p <0.001);. When we analyzed the correlation analysis of parameters associated with myocardial injury with troponin, it showed a good correlation with CRF insert ignore into journalissuearticles values(r = 484, p <0.001);, moderate with procalcitonin insert ignore into journalissuearticles values(r = 274, p <0.001, and weak correlation with age and HT insert ignore into journalissuearticles values(r = 484, p <0.001); = 180, p = 018); insert ignore into journalissuearticles values(r = 159, p = 037);,respectively. DM and D-dimer did not correlate insert ignore into journalissuearticles values(r = 055, p = 472); insert ignore into journalissuearticles values(r = 072 p = 345);.In the multivariate regression analysis, only CRF insert ignore into journalissuearticles values(Odds ratio insert ignore into journalissuearticles values(OD);: 11.062 insert ignore into journalissuearticles values(95% confidence interval insert ignore into journalissuearticles values(CI);: 1.866-65.580);); and reference procalcitonin levels insert ignore into journalissuearticles values(OR: 1.183, 95% CI: 1.014-1.379); predicted myocardial injury. Conclusion: Our study found that LRC did not predict disease progression in Covid-19 patients with myocardial injury.
Keywords : covid 19, , myocardial injury, lymphocyte C reactive protein ratio