Relationship between Cystatin C with some hematological and biochemical parameters in neonatal calf diarrhea

Authors : Mohanad MAKDAM, Yıldıray BASBUGAN

Pages : 79-87

View : 15 | Download : 7

Publication Date : 2020-10-30

Article Type : Research Paper

Abstract :Objectives: The purpose of this research is to determine the relationship between cystatin C insert ignore into journalissuearticles values(Cys-C); and some hematologic and biochemical parameters in neonatal calves diarrhea. Materials and Methods: In this research the animal material of the study was obtained from different breeds, genders and ages insert ignore into journalissuearticles values(0-30 days); 10 samples have been taken from healthy neonatal calves and 22 samples from diarrhea calves which didn′t received any medicine. Otherwise, the general examination has been done for all the calves. Furthermore, by performing etiological examination on the diarrhea calves 3 Giardia, 5 E. coli K99, 8 Coronavirus, 7 Rotavirus and 1 Cryptosporidium have been detected. The levels of hematologic insert ignore into journalissuearticles values(WBC, Neu, Lym, Eo, Mo, RBC, MCV, MCHC, Hct, Hb);, biochemical insert ignore into journalissuearticles values(glucose, TP, Alb, BUN, Cr, CK); and blood gas insert ignore into journalissuearticles values(pH, pO2, pCO2, HCO3-, base, Na+, K+ and Cl-); have been determind for both healthy calves and neonatal calves diarrhea. Results: Depending on the control group, we have observed that the neonatal calves diarrhea hematologic parameters WBC, Neu, Hct, Hb levels insert ignore into journalissuearticles values(p<0.05); and biochemical parameter BUN insert ignore into journalissuearticles values(p<0.01); and Cr insert ignore into journalissuearticles values(p<0.05); level statistically have been increased. On the other hand, Alb insert ignore into journalissuearticles values(p<0.05); and glucose insert ignore into journalissuearticles values(p<0.01); levels have been decreased. In term of blood gas analysis and depending on the control group the level of K+ insert ignore into journalissuearticles values(p<0.05); has been increased, the levels of pH, pO2 and base insert ignore into journalissuearticles values(p<0.05); have been decreased. We evaluate the Cys-C level in the neonatal calves diarrhea and we have found that Cys-C level is statistically increased this was detected comparing to the control group insert ignore into journalissuearticles values(p <0.01);. Conclusion: In this research the obtained level of Cys-C can be used as reference for calves; statistically there is no relationship between Cys-C and some of the hematologic and biochemical parameters, the Cys-C level in the calves diarrhea is an important parameter it can be used to determine the diagnosis, treatment and prognosis of the disease; but still much more research about the topic should be done.
Keywords : Neonatal, calf, Diarrhea, Cystatin C