Investigation of Lipid Profile and Liver Enzymes in Rats Fed on Trans Fats Obtained from Cotton Oil

Authors : Hitame BAŞ, Şeyma UYANIK, Mehmet NİZAMLIOĞLU, Zafer BULUT

Pages : 1-5

View : 13 | Download : 5

Publication Date : 2021-06-11

Article Type : Research Paper

Abstract :It is known that the intake of trans fats, commonly used in the food industry around the world, has a negative effect on healthy and balanced nutrition. The aim of this study was to determine the biochemical changes in an organism following the consumption of cotton oil insert ignore into journalissuearticles values(CO); or trans-fat obtained from cotton oil insert ignore into journalissuearticles values(TF);. A total of 18 Wistar Albino male rats were used. The research was performed in SUDAM unit. Divided into 3 equal groups. The control insert ignore into journalissuearticles values(C); group was fed with a standard rat diet, the CO group was given the standard diet added with 5% CO, and the TF group was given the standard diet added with 5% TF insert ignore into journalissuearticles values(including 30% trans fat);. Ad libitum feeding and water were allowed for 8 weeks of the experimental period. Blood samples were collected on Day 0 by the supraorbital method and on Day 60 by the intracardiac method under anesthesia. Glucose, HbA1c, triglyceride, cholesterol, HDL, LDL, AST, ALT, ALP, GGT, and SOD analyzes were performed. SPSS insert ignore into journalissuearticles values(19.0); program was used for the statistical analyses. Trans fat feeding increased LDL and triglyceride concentrations, decreased HDL concentration, and caused some changes in the levels of the liver enzymes investigated.
Keywords : Cholesterol, cotton oil, lipid profile, trans fat, triglyceride