Quantitative Evaluation of Lung Parenchyma Changes after Treatment in COVID-19 Pneumonia with Volumetric Study in Computed Tomography

Authors : Bahattin ÖZKUL, Furkan Ertürk URFALI, Kıyasettin ASİL

Pages : 528-532

Doi:10.33808/clinexphealthsci.1136688

View : 20 | Download : 6

Publication Date : 2022-06-30

Article Type : Research Paper

Abstract :Objective COVID-19 pandemic, causing approximately 3 million deaths over worldwide, still continues. Effect of COVID-19 pneumonia after treatment on the lungs still not know. Although widely using computed tomography insert ignore into journalissuearticles values(CT); for diagnosing COVID-19 pneumonia, there is not enough study to determine damage of lung after treatment in COVID-19 pneumonia. In this study, our aim was to evaluate lung parenchyma changes in COVID-19 pneumonia after treatment with volumetric study, quantitatively. Methods 25 patients, who has CT at the time of diagnosis insert ignore into journalissuearticles values(CT1); and after 282 days insert ignore into journalissuearticles values(CT2);, and positive polymerase chain reaction test, were included in this retrospective single center study. Total lung volüme insert ignore into journalissuearticles values(TLV); and emphysematous lung insert ignore into journalissuearticles values(ELV); volume of CT1 and CT2 were calculated automatically by using Myrian® XP-Lung and Percentage of emphysematous area insert ignore into journalissuearticles values(PEA); was calculated by dividing ELV by TLV. Differences between CT1 and CT2 in PEA and in TLV and ELV was determined by Wilcoxon and Paired sample t test, respectively. Results Although higher TLV was found in CT2 insert ignore into journalissuearticles values(4216,43 ± 1048,99 cm3); than CT1 insert ignore into journalissuearticles values(3943,22 ± 1177,16 cm3);, there was no statistical significance difference insert ignore into journalissuearticles values(p=0.052); between CT1 and CT2. ELV was statistically insert ignore into journalissuearticles values(p=0.017); higher in CT2 insert ignore into journalissuearticles values(937,22 ± 486,89 cm3); than CT1 insert ignore into journalissuearticles values(716,26 ± 471,65 cm3);. There was a strong indication that the medians were significantly different in PEA insert ignore into journalissuearticles values(p=0,009);. Conclusions Our study showed that there were emphysematous changes in lung parenchyma after COVID-19 pneumonia with CT, quantitatively and in our knowledge, this is the first study that evaluating lung changes quantitative after COVID-19 pneumonia. .
Keywords : COVID 19, Emphysema, Pneumonia, Quantitative, Tomography