A COMPARATIVE STUDY OF ZERO-ORDER AND DERIVATIVE SPECTROPHOTOMETRIC METHODS FOR THE DETERMINATION OF RIVASTIGMINE IN SINGLE DOSAGE FORM

Authors : S. Dermiş GÜNGÖR

Pages : 14-23

Doi:10.1501/Commub_0000000356

View : 11 | Download : 5

Publication Date : 2004-01-01

Article Type : Research Paper

Abstract :In this study zero-order, first and second derivative spectrophotometric methods were applied to the determination of Rivastigmine insert ignore into journalissuearticles values(RVT); in capsules. UV-spectrum, first derivative and second derivative spectrums of RVT were plotted in the spectral range of 230-280 nm. Zero-order, first derivative and second derivative absorbance values were measured at maximum wavelenghts for this three methods. Lineer calibration graphs were found in the working range of 0.2 mM -1.0 mM insert ignore into journalissuearticles values(80 - 400 pg ml1);. All three methods were statistically compared with each other and significant results were obtained
Keywords : A COMPARATIVE STUDY, ZERO ORDER, DETERMINATION OF RIVASTIGMINE