Effects of Tribulus terrestris, Avena sativa and White Ginseng on Adiponectin, Leptin, Resistin, Fatty Acid Binding Protein 4, Homocysteine and Paraoxonase-1 Levels in Hypercholesterolemic Rats

Authors : Ahmet NALBANT, Ali BİLGİLİ, Basak HANEDAN, Mehmet AKDOĞAN

Pages : 135-142

Doi:10.38093/cupmap.829184

View : 11 | Download : 9

Publication Date : 2020-12-24

Article Type : Research Paper

Abstract :This study was aimed to evaluate the effects of Tribulus terrestris insert ignore into journalissuearticles values(TT);, Avena sativa insert ignore into journalissuearticles values(AS);, white ginseng insert ignore into journalissuearticles values(WG);, and a triple combination insert ignore into journalissuearticles values(TC); powder on adipokines, homocysteine and paraoxonase-1 levels in hypercholesterolemic rats. Hypercholesterolemia in rats was induced by diet added 2% cholesterol. Herbal treatment groups consisted of Group III insert ignore into journalissuearticles values(TT);, Group IV insert ignore into journalissuearticles values(AS);, Group V insert ignore into journalissuearticles values(WG); and Group VI insert ignore into journalissuearticles values(triple combination of TT, AS, and WG);. Significant increase in total cholesterol, LDL-C, homocysteine, leptin and resistin levels insert ignore into journalissuearticles values(P 0.05); were found in hypercholesterolemic rats. The treatment combination with TT, AS and WG significantly reduced total cholesterol, LDL-C, homocysteine, leptin and resistin levels in hypercholesterolemic rats insert ignore into journalissuearticles values(P<0.05);. In conclusion, it was found that TT, AS and WG had positive effects on reversing the effects of hypercholesterolemia in rats. The combination treatment with TT, AS and WG may have therapeutic effects in the treatment of hypercholesterolemia.
Keywords : Hypercholesterolemia, Adipokines, Homocysteine, Paraoxonase 1, Herbal treatment