Can the Neutrophil/Lymphocyte Ratio and Platelet/Lymphocyte Ratio Be Used to Predict the Risk of Ureteral Stricture Following Ureteroscopy?

Authors : Reha Ordulu, Mustafa Aydın, Emrah Küçük, Hakan Yıldız, Mahmut Ulubay, Ekrem Akdeniz, Mustafa Kemal Atilla

Pages : 99-107

Doi:10.54233/endourolbull-1526700

View : 42 | Download : 67

Publication Date : 2024-09-29

Article Type : Research Paper

Abstract :Objective: The purpose of this study was to investigate whether the neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratio (PLR) can be used to predict the development of ureteral stricture or difficult ureter in patients who had previously undergone endoscopic upper urinary tract surgery. Material and Methods: This observational study was performed between April 2022 and April 2023 at the Samsun Training and Research Hospital Urology Department, Türkiye. One hundred thirty patients who had undergone prior endoscopic upper urinary tract surgery were included. These were divided into two groups, with (Group 1) and without (Group 2) ureteral stricture. The diagnosis of ureteral stricture was based on direct endoscopy or retrograde pyelography. The groups’ sociodemographic characteristics, clinical data, and NLR and PLR values were then compared. Results: The patients’ mean ages were 49.89±14.40 years in Group 1 and 48.92±14.60 in Group 2 (p = 0.704). No statistically significant differences were observed between the groups in terms of sex, body mass index, or comorbidity. However, significant differences were determined in terms of passage of kidney stones and numbers of surgical procedures performed (p = 0.001 and p <0.001, respectively). The groups’ NLR values were 2.62 (0.75-9.18) and 2.29 (0.80-6.67), and their PLR values were 136.57 (55.02-475.45) and 118.66 (37.50-244.17), respectively. The differences between the groups were not statistically significant (p = 0.139 and p = 0.076, respectively). Conclusion: Although NLR and PLR values were higher in the group with ureteral stricture in this study, that elevation was not statistically significant. The results show that the evaluation of NLR and PLR values are not useful in predicting ureteral stricture in patients who have previously undergone endoscopic upper urinary tract surgery.
Keywords : Üreter darlığı, zor sıkı üreter, nötrofil lenfosit oranı, platelet lenfosit oranı