Lactate/Albumin Ratio as a Predictor of Mortality in Patients with Crimean-Congo Hemorrhagic Fever

Authors : Yusuf Kenan Tekin, Şimşek Çelik

Pages : 339-345

Doi:10.53424/balikesirsbd.1422074

View : 27 | Download : 35

Publication Date : 2024-08-28

Article Type : Research Paper

Abstract :Objective:This study aimed to determine the relationship of lactate/albumin (L/A) ratio with prognosis and fatality in CCHF patients. Materials and Methods: A total of 260 patients diagnosed with CCHF between January 2019 and December 2022, 36 of whom were deceased and 224 of whom were alive, were retrospectively included in the study. The findings of survivor and non-survivor patients were compared. Results: There was no significant difference between the groups in terms of age and gender. While albumin, glucose and platelet levels were quite low in the patient group who died due to CCHF (p<0.001); White blood cells, urea nitrogen, creatinine, alanine aminotransferase, aspartate aminotransferase, sodium, lactate, L/A ratio and high-sensitivity C-reactive protein in the blood were found to be significantly high (p<0.05). In the ROC analysis, the highest sensitivity and specificity were calculated as the L/A ratio. Conclusion: We found that the L/A ratio can be used as a tool to predict fatality in CCHF patients. In addition, the L/A ratio was more significant in predicting fatality than serum albumin and serum lactate levels alone.
Keywords : Acil Servis, Kırım Kongo Kanamalı Ateşi, Laktat Albumin Oranı, Fatalite