Implications of Gastric Diverticulum in the Incidence of Metaplasia: An Analysis of 37 Cases

Authors : Ali MUHTAROĞLU, Ersin KULOĞLU, Kubilay İŞSEVER, Ahmet DÜLGER

Pages : 632-7

Doi:10.37990/medr.1328204

View : 22 | Download : 33

Publication Date : 2023-09-18

Article Type : Research Paper

Abstract :Aim: The present study aimed to investigate the potential association between gastric fundus diverticulum and metaplasia by retrospectively analysing patient data and biopsy results. Material and Methods: 37 patients with gastric fundus diverticulum were examined, with their data compared to a control group of 50 patients without it. All diagnoses were made endoscopically. Demographic information, laboratory parameters, and endoscopic biopsy results were compared between the groups. Results: No significant differences were identified between the two groups concerning several laboratory parameters. However, there were significant differences in lymphocytes, urea, albumin, Na, and K values insert ignore into journalissuearticles values(p 0.05);, while a notable difference was seen in the distribution of metaplasia insert ignore into journalissuearticles values(p<0.05);. Metaplasia positivity was found to be 16% in patients without gastric diverticulum and 43.2% in patients with gastric diverticulum. Conclusions: This study found a higher prevalence of metaplasia positivity in patients with gastric diverticulum than those without. These findings suggest a potentially significant link between the gastric diverticulum and the occurrence of metaplasia, which warrants further research to better understand the underlying mechanisms and implications for patient management.
Keywords : gastric diverticula, metaplasia, gastric biopsy, endoscopy, gastroenterology