The Role of Chlorogenic Acid in Alleviating Intestinal Ischemia/Reperfusion-Induced Lung Injury

Authors : Ayhan TANYELİ, Derya GÜZEL, Fazile Nur EKİNCİ AKDEMİR, Ersen ERASLAN, Mustafa Can GÜLER

Pages : 59-64

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Publication Date : 2020-09-30

Article Type : Research Paper

Abstract :Aim: Here, Chlorogenic acid insert ignore into journalissuearticles values(CA); was examined in intestinal ischemia reperfusion insert ignore into journalissuearticles values(I/R);-induced lung injury. Material and Methods: 4 experimental rat groups were created insert ignore into journalissuearticles values(n=8);: sham, I/R and CA treatment groups. At the end of the experimental process, rats were immolated and lung tissues were excised. Results: Oxidant parameters increased and antioxidant activity declined in I/R group compared to sham group. CA treatments reversed these parameters. Discussion and Conclusion: Different doses of the CA prevented intestinal I/R-induced lung injury in experimental animals.
Keywords : Intestinal ischemia reperfusion, lung, Chlorogenic acid, oxidative stress, inflammation, rat