Vestibular Evoked Myogenic Potential Abnormalities in Early and Late Stage Parkinson Patients

Authors : Sinan GÖNÜLLÜ, Suat KAMİSLİ, Cemal ÖZCAN

Pages : 13-18

Doi:10.56766/ntms.1097652

View : 13 | Download : 5

Publication Date : 2023-01-30

Article Type : Research Paper

Abstract :ABSTRACT Aim: Loss of balance can be seen in idiopathic Parkinson\`s disease insert ignore into journalissuearticles values(IPD); There are only a few studies in the literature in which brainstem involvement in IPD has been researched with neurophysiological tests such as vestibular evoked myogenic potential insert ignore into journalissuearticles values(VEMP);. In this study, it was investigated whether there is a difference in the results of VEMP testing in early or late stage of IPD. Material and method: The IPD cases were classified as early stage and late stage according to the Hoehn-Yahr scale. The presence of a positive wave with a latency of P13 and a negative wave with a latency of N23 was investigated as the first reflex response The latencies of these potentials and the absolute amplitude of the P13-N23 component were measured. The VEMP results of the patients with early and late stage IPD were compared with those of the control group. Results: The right P13 latency mean value in the late stage patient group was significantly prolonged than in the early stage patient group and the control group. The right P13-N23 amplitude mean value of the late and early stage patient groups was significantly smaller than that of the control group insert ignore into journalissuearticles values(p < 0.002 and p < 0.001, respectively);. Among the patients with IPD, the P13 latency was statistically increased in those with a fall history than in those without a fall history. In conclusion, this study indicates that the VEMP pathway is affected over time especially in patients with late stage Parkinson’s disease.
Keywords : c VEMP, neurophysiology, brainstem, early stage Parkinsons disease, late stage Parkinsons disease, Parkinsons disease