HPV Prevalence and Risk of Premalignant and Malignant Lesions in Women with Asymptomatic Cervical Erosion: A Populatıon-Based Study

Authors : Pelin Oyardi, Funda Dağistanli, Merve Ecem Albayrak, Mehmet Kayhan, Mustafa Ayhan Ekici

Pages : 207-212

Doi:10.47493/abantmedj.1365241

View : 109 | Download : 92

Publication Date : 2023-12-29

Article Type : Research Paper

Abstract :Objective: To evaluate the prevalence of Human papillomavirus (HPV) and the risk of cervical premalignant and malignant diseases in women with cervical erosion. Materials and Methods: The results of 32649 women who screened for cervical cancer between January 2014 and December 2019 were retrospectively analyzed. We compared the results of HPV-positive and HPV-negative women with cervical erosion using the Kruskal-Wallis test and Chi-square test. Results: Of the 32649 women who had cervical cancer screening, 2566 had cervical erosion, and 1585 (4.85%) had HPV positivity. HPV was found positive in 126 (4.91%) women with cervical erosion, and no significant difference in the incidence of HPV positivity in asymptomatic women with and without cervical erosion (p=0.112). As in the general population, in women with cervical erosions, HPV-16 and HPV-18 were found to be the most common. Abnormal cervical cytology was found in 217 (0.72%) women without cervical erosion and 31 (1.21%) women with cervical erosion, which was significantly higher than in women without cervical erosion (p=0.045). There was no significant difference between those with and without cervical erosion in terms of cervical intraepithelial neoplasia (CIN)-1, CIN-2, CIN-3, low-grade squamous intraepithelial lesions, high-grade squamous intraepithelial lesions, in situ cancer, and total abnormal cervical pathology results. Conclusion: The incidence of HPV and the likelihood of cervical pathology in asymptomatic women with cervical erosion do not differ from the general population.
Keywords : Servikal erozyon, Ektropiyon, Servikal kanser, HPV, CIN