Estimation of Birth Weight from HbA1c and Glucose Levels in Diabetic Pregnancies

Authors : Kamuran SUMAN, Ebru GÖK, Zafer BÜTÜN, Pınar BÜTÜN, Musa BÜYÜK, Murat SUMAN

Pages : 222-226

Doi:10.33631/sabd.1199501

View : 14 | Download : 4

Publication Date : 2023-05-10

Article Type : Research Paper

Abstract :Aim: The aim of this study was to investigate the sensitivity of baby birth weight estimation in relation to HbA1c levels of pregnant women diagnosed with pre-gestational diabetes mellitus insert ignore into journalissuearticles values(PGDM); and gestational diabetes mellitus insert ignore into journalissuearticles values(GDM);. Material and Methods: 105 patients who met the criteria agreed to participate in our study, of whom 7 were type 1 DM and 32 were type 2 DM. The pregnancy history of the patients who agreed to participate was obtained with a lot of demographic information as well as weight gains during pregnancy, HbA1c and fasting blood glucose levels. Results: Fasting glucose values were measured at 28 and 32 weeks of gestation. The blood glucose values that we measured one hour after satiation and HbA1c were higher in the PDGM group than in the GDM group. There was no significant difference between weight gain and BMI values. We used ROC curve analysis to test the predictive power of fasting and postprandial blood glucose levels or weight gain during pregnancy in our patients with GDM for LGA babiesinsert ignore into journalissuearticles values(LGA); insert ignore into journalissuearticles values(AUC: 0.663, %95 CI [0.526, 0.800], AUC: 0.678, %95 CI [0.540, 0.816], AUC: 0.677, %95 CI [0.548, 0.805], respectively);.In addition, ROC analysis was used in evaluating fasting blood glucose measurements, 1-hour postprandial blood glucose measurements, and HbA1c levels to predict LGA.insert ignore into journalissuearticles values(AUC: 0.889, %95 CI [0.782, 0.996], AUC: 0.893, %95 CI [0.737, 1.000], AUC:0.931, %95 CI [0.807, 1.000], respectively);. Conclusion: In both healthy people and pregnant women, it is important to keep blood glucose levels within normal limits. In pregnant women diagnosed with PDGM or GDM, this is even more important as the welfare of the baby is considered. LGA deliveries can be avoided in pregnant women with PDGM by close monitoring of postprandial blood glucose and HbA1c levels. Close monitoring of GWG is also beneficial in the follow-up of pregnant women diagnosed with GDM.
Keywords : HbA1c, Açlık glukoz düzeyi, Doğum ağırlığı