Patency and Survival in Patients Undergoing Revascularization for Peripheral Arterial Disease

Authors : Ömer Faruk Rahman, Erdem Ali Özkısacık

Pages : 215-223

Doi:10.33631/sabd.1401456

View : 23 | Download : 61

Publication Date : 2024-05-22

Article Type : Research Paper

Abstract :Aim: Peripheral arterial disease is a progressive, and chronic disease caused by atherosclerosis, and characterized by narrowing, or occlusion of the arterial structures of the lower extremities, which can lead to high morbidity and mortality. The aim of this study is to investigate the short and medium-term patency, and survival outcomes of different peripheral arterial revascularization techniques. Material and Methods: Patients undergoing revascularization for lower extremity arterial disease between January 2015 and August 2019 were retrospectively analyzed. Patients were divided into three groups according to the type of revascularization: endovascular, surgical, or hybrid. Major amputation, occlusion, and death were the primary endpoints. Expected primary patency and overall survival rates were estimated using Kaplan-Meier analyses. Results: The study included 285 patients and 338 revascularization procedures. There was no difference in primary outcome between treatment groups (p=0.080). Improvement in Rutherford category was observed in 57.1% of patients after revascularization. There was no difference between the groups in terms of change in Rutherford category (p=0.230). Expected primary patency rates were significantly lower in patients with chronic limb-threatening ischemia, and in patients with chronic renal failure (respectively; p<0.001, p=0.02). There was no difference in expected primary patency between the groups (p=0.069). Overall survival rates were lower in the presence of chronic limb-threatening ischemia, chronic renal failure and atrial fibrillation (respectively; p=0.013, p=0.010, p<0.001). Conclusion: In our study, chronic limb-threatening ischemia and renal failure were associated with worse survival and lower primary patency rates. There was no difference in survival between revascularization groups. Atrial fibrillation was associated with worse survival.
Keywords : Ampütasyon, Endovasküler, Periferik arter hastalığı, Revaskülarizasyon