Simultaneous search of multiple groups of antibiotics and their different components in the honey

Authors : Namık BİLİCİ, Yılmaz ALTUNER, Erol KABİL, Hatice Kübra KOÇ TOPÇUOĞLU, Ümit TOPÇUOĞLU

Pages : 15-33

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Publication Date : 2019-08-30

Article Type : Research Paper

Abstract :The honey is a bee insert ignore into journalissuearticles values(Apis mellifera); product formed by the chemical change of the nectars that the bees collect from the flowers. Honey is more or less affected by the antibiotics used in bee diseases. This contagion has vital importance in terms of public health. For this reason, simultaneous and rapid detection of different antibiotic groups in the remnants of used veterinary medications is important. Simultaneous identification of different groups of antibiotics depends on the detection method of each group, the performances of the devices, and the success of the validation. This study was carried out to realize the identification, validation and method development of the multiplex-group antibiotic residues, in the direction of EU Directive 2002/657 EEC. A different method has been developed for a total of 35 antibiotics from many groups, and the detection limits, deviations, LOD, LOQ and validations are presented. It has been identified in this study that the simultaneous detection and validation of multiplex-groups of antibiotics, which have not yet been routinely practised, is possible. With this study, a unique method and a validation technique, which may be used by national competent authorities, has been developed.
Keywords : Honey, Residue, Antibiotic, Honeybee