Examination of anti-oxidant properties and molecular docking parameters of some compounds in human body

Authors : Burak TÜZÜN

Pages : 76-87

Doi:10.33435/tcandtc.781008

View : 12 | Download : 4

Publication Date : 2020-12-15

Article Type : Research Paper

Abstract :There are many hormones and molecules in the human body. Many of these take place in different jobs and tasks. Some of these hormones are serotonin insert ignore into journalissuearticles values(A1);, testosterone insert ignore into journalissuearticles values(A2);, dopamine insert ignore into journalissuearticles values(A3);, adrenaline insert ignore into journalissuearticles values(A4);, methylcytosine insert ignore into journalissuearticles values(A5); and creatine insert ignore into journalissuearticles values(A6);. The anti-oxidant properties of these molecules in both gas and water phases of the HF/6-31ginsert ignore into journalissuearticles values(d,p); basis set were calculated with the Gaussian package program. After this process, molecular docking calculations were made to compare the activities of molecules against proteins with anti-oxidant properties whose name are human peroxiredoxin-5 insert ignore into journalissuearticles values(HP5); and bovine xanthine oxidase insert ignore into journalissuearticles values(BXO);, were compared.
Keywords : antioxidant, molecular docking, DFT, human body, hormone