Tiroid Patolojisinde Proteomik Yaklaşımlar

Authors : Yasemin UÇAL, Aysel OZPİNAR

Pages : 357-362

View : 24 | Download : 13

Publication Date : 2019-09-01

Article Type : Other Papers

Abstract :Thyroid cancer is the most common endocrine malignancy, of which the incidence has increased worldwide in the past years. The most reliable and inexpensive method for establishing the histopathological diagnosis of thyroid nodules is Fine Needle Aspiration Biopsy FNAB . However, the lack of discrimination distinctive criteria in differential diagnosis leads to the failure of the successful diagnosis of some nodules. For this purpose, several molecular techniques have been developed and several molecules were targeted for the differential diagnosis of thyroid nodules. However, genetic mutations or cell surface markers that might contribute to the differential diagnosis are not widely used due to the differences in prevalence
Keywords : Thyroid pathology, proteomics, mass spectrometry