The Usage and Efficiency of Drug Eluting Stents in Vertebral Ostial Stenosis

Authors : Burcu ERKAN, Serdar GEYİK, Kıvılcım YAVUZ, Işıl SAATÇİ, Saruhan ÇEKİRGE

Pages : 564-573

Doi:10.31067/acusaglik.850835

View : 38 | Download : 10

Publication Date : 2021-07-01

Article Type : Research Paper

Abstract :Objectives: Extracranial vertebral artery atherosclerosis is an insidious and hazardous disease. With technological development and accumulating experience, antiproliferative drug eluting stents became a viable option for reducing the instent restenosis of the origin of the vertebral artery. Here, we evaluated the technical success rates, efficiency, clinical and angiographic results of the usage of drug eluting stents in vertebral ostial stenosis. Patients and Methods: 28 stents were implanted in 24 patients with vertebral artery origin stenosis. Digital substraction angiographic or CT angiographic follow-up was made at 6, 12 and 24 months. Results: Paclitaxel eluting stents were placed with high technical success for the treatment of vertebral artery origin stenosis. There was no procedure related mortality. However one patient scummed to death due to aspiration pneumonia for a basiller artery stroke with successful stenting and thrombolysis procedure. There was only one limited subclavian artery dissection in a patient insert ignore into journalissuearticles values(%4.1); during the procedure which was managed conservatively. One stent insert ignore into journalissuearticles values(%3.7); had instent restenosis on early period insert ignore into journalissuearticles values(6th month); and one patient insert ignore into journalissuearticles values(%4.1); had recurrent neurological symptoms on follow-up insert ignore into journalissuearticles values(9th month);. In a median follow-up of 13 months insert ignore into journalissuearticles values(6-25 months); none of the patients had late stent thrombosis. Conclusion: Vertebral artery ostial stenosis can be treated effectively and safely with high technical success and low instent restenosis rates with paclitaxel drug eluting stents. With low restenosis rates the antiproliferative drug eluting stents are an option for reducing the vertebral artery instent restenosis.
Keywords : Vertebral artery origin, stenosis, paclitaxel, drug eluting stent