The effect of Thymus vulgaris essential oil on the formation of Candida albicans biofilm on denture base materials: An in vitro study

Authors : Leyla Güven, Nurdan Polat Sağsöz, Figen Orhan, Neslihan Macit Kavaz

Pages : 97-105

Doi:10.30569/adiyamansaglik.1457922

View : 78 | Download : 56

Publication Date : 2024-08-30

Article Type : Research Paper

Abstract :Aim: This study aims to evaluate the antifungal properties of Thymus vulgaris (thyme) essential oil (TVEO) on Candida albicans-infested polymethyl methacrylate (PMMA) denture base materials and identify the volatile components of T. vulgaris essential oil. Materials and Methods: The investigation involved establishing C. albicans\'s presence on resin surfaces manufactured in 1x1x0.1 cm size. The resin surfaces on which the C. albicans biofilm had formed were then soaked in a 2% and 5% solution of TVEO and the effect on the amount of C. albicans colonisation were evaluated. The volatile components of TVEO were determined using the GC-MS method. Results: Solutions prepared from 2% and 5% TVEO showed better antifungal activity than Corega. The major components detected by GC-MS in the TVEO were carvone 61.36%, linalool 8.32%. Conclusion: TVEO, showed significant antifungal effects on PMMA resin surfaces. This oil can, therefore, be recommended as an inexpensive, uncomplicated and efficient natural cleaning agent for those wearing dentures.
Keywords : Antifungal aktivite, C Albicans, Protez temizleyiciler, Thymus vulgaris