Relationship Between Systemic Immune Inflammation Index and Prognosis in Patients with COVID-19

Authors : Sebnem NERGİZ, Onder OZTURK

Pages : 612-618

Doi:10.5798/dicletip.1220894

View : 12 | Download : 4

Publication Date : 2022-12-19

Article Type : Research Paper

Abstract :Objectives: Inflammation and coagulation perform a substantial act in the pathophysiology of COVID-19 cases. The systemic immune-inflammation index insert ignore into journalissuearticles values(SII); is a novel prognosis and inflamation index. In this study, we aimed to research the relation between SII and prognosis in COVID-19 patients. Methods: 315 cases insert ignore into journalissuearticles values(males, 136 ; females, 179 ; 63.2 ± 11.4 years); with positive PCR and lung tomography evidences compatible with COVID-19 pneumonia were recorded in the research. Patients were separated into 2 groups according to the mortality insert ignore into journalissuearticles values(Group 1; Surviving patients, Group 2; Ex patients);. Clinical, demographic, and laboratory datas for whole patients were registered Laboratory datas were measured from blood parameters taken during hospitalization. The SII was calculated as “ SII = neutrophil count × platelet count / lymphocyte count ”. Results: The mean hospital stay of the patients is 12 insert ignore into journalissuearticles values(5-26); days. When the patients were assessment of according to clinical features, an important distinction was found between the two groups according to age, gender, cardiovascular disease, chronic renal failure, neurolvascular disease, and diabetes mellitus. When the patients were evaluated according to laboratory parameters, white blood cells, neutrophils, creatinine, D-Dimer, ferritin, CRP values were observed to be significantly higher in Group 2 patients than Group-1 patients. However, lymphocyte count, serum potassium level, albumin and calcium levels were observed to be significantly lower in Group-2 patients than in Group-1 patients. SII level was significantly higher in Group 2 patients than Group-1 patients insert ignore into journalissuearticles values(1813.4 ±118.7 vs 978.2 ± 93.1, p<0.001);. Conclusions: Our results suggested that a relation between a higher SII value and a death in COVID-19 patients. As a simple parameter, SII is a significantly estimating of death in COVID-19 patients.
Keywords : COVID 19, inflammation index, prognosis