Effect of cardio-gastric interaction on atrial fibrillation in GERD patients

Authors : Serhat GÜNLÜ, Eşref ARAÇ, Adem AKTAN, Fethullah KAYAN, Bernas ALTINTAŞ, Mehmet Zülkif KARAHAN

Pages : 304-310

Doi:10.5798/dicletip.1360607

View : 26 | Download : 41

Publication Date : 2023-09-15

Article Type : Research Paper

Abstract :Objective: Atrial fibrillation insert ignore into journalissuearticles values(AF); and gastroesophageal reflux disease insert ignore into journalissuearticles values(GERD); are very common in daily clinical practice. Post-prandial AF episodes have been reported in GERD patients. Although it was reported in previous studies that it was caused by sympathovagal imbalance, there are no studies on cardiac conduction system involvement. In this study, we aimed to evaluate whether the risk of developing AF increases in untreated GERD patients with non-invasive electrophysiological tests. Methods: The research was prospectively performed. Endoscopy was performed on the individuals due to reflux complaints. ECG was recorded at 25mm/s and 10 mm/mV amplitude, and 24-hour Holter ECG insert ignore into journalissuearticles values(three-channel; V1, V2, and V5); was performed. ECG parameters were measured and Holter ECG results were analyzed. Results: A total of 120 individuals, 60 patients and 60 controls, were included. No significant statistically differences existed between groups for hypertension, diabetes, smoking, or dyslipidemia insert ignore into journalissuearticles values(p>0.05);. In terms of heart rate, Pmax, Pmin, QTd, and QTcd, there were no significant differences across the two groups insert ignore into journalissuearticles values(p>0.05);. P-wave dispersion insert ignore into journalissuearticles values(Pd); was substantially higher in the study group insert ignore into journalissuearticles values(p=0.014);. Comparing the heart rate variabilities of 24-hour Holter ECG recordings across the groups, the standard deviation of R-R intervals insert ignore into journalissuearticles values(SDNN); was substantially higher in the study group insert ignore into journalissuearticles values(p<0.001);. Low Frequency insert ignore into journalissuearticles values(LF); and LF/HF were significantly higher in the control group insert ignore into journalissuearticles values(p<0.001 and p=0.003, respectively);. AF was detected in nine individuals on Holter ECG. Conclusion: Pd duration and risk of developing AF were higher in GERD patients.
Keywords : Atrial fibrillation, heart rate variability, gastroesophageal reflux, Holter ECG