Investigation of the Frequency of Rotavirus and Enteric Adenovirus Infections in Patients with Acute Gastroenteritis

Authors : Hacer Özlem Kalaycı, Mustafa Kerem Çalgın

Pages : 325-331

Doi:10.46332/aemj.1488950

View : 15 | Download : 16

Publication Date : 2024-12-17

Article Type : Research Paper

Abstract :Purpose: Rotavirus and enteric adenovirus are common viral agents associated with severe clinical symptoms in gastroenteritis. Rotaviruses are responsible for 20-40% of acute gastroenteritis cases worldwide, which result in millions of deaths each year. This study was conducted to determine the frequency of rotavirus and enteric adenovirus infections in patients diagnosed with acute gastroenteritis at our hospital, and to investigate the distribution of positivity based on age groups, gender, and seasons. Materials and Methods: A total of 5210 stool samples were analyzed using the immunochromatographic method. The patients\\\' data were evaluated retrospectively. Statistical analyses were performed using the MedCalc statistical software (version 20.009; Ostend, Belgium). Results: Rotavirus positivity was detected in 261 of the samples (5%), with the highest positivity observed in children aged 25-60 months and during the summer months. Regarding enteric adenoviruses, positivity was detected in 69 samples (1.3%), with the highest positivity found in the 0-24 month age group. When the distribution of rotavirus and enteric adenovirus positivity was examined according to seasons, a statistically significant association was found in the summer season. No statistically significant relationship was found between gender and viral antigen positivity. Conclusion: In conclusion, the investigation of rotavirus and enteric adenovirus antigens in stool samples is important for obtaining epidemiological data and preventing unnecessary antibiotic use.
Keywords : antijen, dışkı, immünokromatografik