Evaluation of aflatoxin M1 content in milk and dairy products by high-performance liquid chromatography in Tehran, Iran

Authors : Nazanin SHABANSALMANİ, Mohammadhosein MOVASSAGHGHAZANİ

Pages : 435-443

Doi:10.29050/harranziraat.1247936

View : 46 | Download : 57

Publication Date : 2023-09-27

Article Type : Research Paper

Abstract :Aflatoxin M1 insert ignore into journalissuearticles values(AFM1); is the most important aflatoxin in milk and dairy products, which is carcinogenic and hepatotoxic. This study aimed to evaluate the AFM1 content in the milk and distributed dairy products in Tehran. 75 samples, including 15 samples of raw milk, 15 samples of pasteurized milk, 15 samples of ultra-high temperature milk, 15 samples of pasteurized yogurt, and 15 samples of pasteurized cheese, were collected from October to December 2020 in Tehran by simple random sampling. The dietary exposure or estimated dietary intake insert ignore into journalissuearticles values(EDI); and hazard index insert ignore into journalissuearticles values(HI); were calculated for milk and dairy product consumers. The AFM1 content in the samples was determined by using high-performance liquid chromatography insert ignore into journalissuearticles values(HPLC); along with a fluorescence detector. AFM1 was observed in all samples. The values of AFM1 in all samples were higher than the acceptable range determined by the European Union. 100% of milk and yogurt samples and 82% of cheese samples exceeded the Iranian maximum limit insert ignore into journalissuearticles values(100 ng kg-1 in milk and yogurt, and 250 ng Kg-1 in cheese);. Mean AFM1 content in raw milk samples, pasteurized milk samples, UHT milk samples, pasteurized yogurt samples, and pasteurized cheese samples were 337±17.7, 306±15.5, 305±17.4, 320±17.6, and 309±18.5 ng Kg-1, respectively. The highest value of HI was observed in children of Tehran, Iran. Based on the results, the aflatoxin content in milk and distributed dairy products in Tehran in the autumn is inconvenient. It is recommended that the aflatoxin levels should be measured at different times of the year, especially in raw milk, and feed monitoring is intensified for contamination with toxin-producing molds.
Keywords : Süt, Süt Ürünleri, Aflatoksin M1, HPLC, Tahran