Evaluation of Factors Associated With Mortality in Catheter-Related Urinary Tract Infections: A 5-Year Retrospective Study

Authors : İlker ÖDEMİŞ, Ayfer İMRE

Pages : 145-152

Doi:10.17517/ksutfd.1146548

View : 12 | Download : 6

Publication Date : 2023-03-16

Article Type : Research Paper

Abstract :Objective: The aim of the study is to evaluate the relationship between mortality and epidemiological factors, comorbid conditions, antibiotic resistance, empirical antimicrobial therapy, and laboratory parameters in catheter-associated urinary tract infections insert ignore into journalissuearticles values(CAUTI);. Materials and Methods: A retrospective cohort study was designed in patients aged ≥18 years admitted to intensive care unit between 1st Jan 2015 and 1st Jan 2020. The primary endpoint was death within the first 28 days of admission, while the secondary endpoint was survival after 28 days. p value <0.05 was considered statistically significant. Results: A total of 375 patients with a median age of 78 were included in the study; 198 insert ignore into journalissuearticles values(52.8%); were female. The most commonly detected microorganisms were Escherichia coli insert ignore into journalissuearticles values(50.9%); and Enterococcus faecalis insert ignore into journalissuearticles values(16.8%);. Resistance to third generation cephalosporin, ciprofloxacin, and meropenem was found in 41.3%, 40%, and 8.6% of Gram-negative bacteria, respectively. Vancomycin resistance was detected in 0.3% of the Gram-positive bacteria. The mortality rate was 58.1%. Factors associated with an increased risk of mortality were age ≥65 years, presence of malignancy, mechanical ventilation, APACHE II score ≥20, and a diagnosis of septic shock. The only factor associated with the lower mortality risk was the detection of E. coli in culture. Conclusion: It was determined that aging, malignancy, clinical scoring systems and microbiological results had an effect on mortality. Considering the results of this study together with the infection control measures, and treatment recommendations in the guidelines, we think that mortality due to CAUTI can be reduced.
Keywords : Üriner kanal enfeksiyonları, idrar yolu kateterleri, ölüm oranı, antibiyotikler, ilaç direnci, kateter kaynaklı enfeksiyonlar