Role of presepsin in predicting sepsis and mortality in COVID-19 pneumonia

Authors : Veysi Siber, Hatice Kübra Siber, Murat Aysin, Sertaç Güler, Özlem Özbaş Demirel, Dursun Bugra Dereyurt, Sümeyye Alkan, Yavuz Otal, Yahya Kemal Günaydin, Mehmet Okumuş

Pages : 95-100

Doi:10.35514/mtd.2024.100

View : 62 | Download : 112

Publication Date : 2023-12-31

Article Type : Research Paper

Abstract :ABSTRACT Introduction/Background: We aimed to investigate the prognostic significance of Presepsin(PSP) in the patients with Coronavirus Disease 2019 pneumonia who admitted to the emergency department. Material and Method: This study was conducted as a prospective, case-controlled, observational study. 123 patients with a diagnosis of COVID-19 pneumonia were chosen for the case group and 123 volunteers were enrolled as a control group. 62 of the patients were classified into the sepsis group and 61 patients were placed into the non-sepsis group. The follow-up and treatment of the patients were carried out according to the COVID-19 Severe Pneumonia, ARDS, Sepsis, and Septic Shock Management Guideline of the Turkiye Ministry of Health. The PSP level was studied in patients with and without sepsis diagnosed with COVID-19 pneumonia. Results: There was no statistically significant difference between the control group, the sepsis group, and the non-sepsis group when the PSP values were compared. However, when the ROC curve was studied for the case group, a statistically significant difference between the survivors and non-survivors was discovered (p<0.05). Conclusion: No statistically significant distinction in PSP values between the control group and the septic and non-septic patient groups with COVID-19 pneumonia was found. However, PSP values were shown to be statistically significant in mortality of COVID-19 pneumonia and survival. Keywords: COVID-19, Emergency Medicine, Human Presepsin Protein, Pneumonia, Sepsis
Keywords : Acil Tıp, COVID 19, Human Presepsin Protein, Sepsis, Pnömoni